17959-64-7

Usage

Uses

Used in Pharmaceutical Industry:
2-Phenoxyethylamine hydrochloride is used as a precursor in the synthesis of various drugs and organic compounds, contributing to the development of new medications and therapeutic agents.
Used in Chemical Industry:
In the chemical industry, 2-PEA HCl serves as a key intermediate in the production of a range of organic compounds, facilitating the creation of diverse chemical products.
Used in Therapeutic Applications:
2-Phenoxyethylamine hydrochloride is used as a vasodilator for its ability to widen blood vessels, potentially improving blood flow and reducing blood pressure.
Used in Neurological Disorder Treatment:
2-PEA HCl is being studied for its potential use in the treatment of neurological disorders, suggesting a role in managing or alleviating symptoms associated with such conditions.

Upstream product

• 1758-46-9 2-phenoxyethanamine 
• 108-95-2 phenol 
• 921596-28-3 tert-butyl (2-phenoxyethyl)carbamate 

Downstream Products

• 40077-26-7 2-[(2-Phenoxy-ethylamino)-methyl]-3,4-dihydro-2H-naphthalen-1-one 
• 64463-83-8 1-(2-Phenoxy-ethylamino)-3-p-tolyloxy-propan-2-ol 
• 64463-90-7 1-(2-Bromo-phenoxy)-3-(2-phenoxy-ethylamino)-propan-2-ol 
• 64596-96-9 1-(4-Benzyloxy-phenoxy)-3-(2-phenoxy-ethylamino)-propan-2-ol 
• 64463-54-3 1-Phenoxy-3-(2-phenoxy-ethylamino)-propan-2-ol 
• 155768-97-1 2-chloro-N-(2-phenoxyethyl)adenosine 
• 1205561-38-1 2-iodo-4-methyl-N-(2-phenoxyethyl)-1,3-thiazole-5-carboxamide 
• 1353573-75-7 5-{[(2-phenoxyethyl)amino]methyl}-2,2-diphenylcyclopentan-1-one 
• 22303-44-2 5-amino-3-(2-phenoxy-ethyl)-[1,2,3]oxadiazolium betaine 

Relevant academic research and scientific papers

Double - (to - alkoxybenzyl propenone) glutathione - S - transfers the sulfur of the enzyme dives inhibitors

The invention discloses a bis-(p-alkoxy benzene acrylketone) like glutathione-S-transferase potential inhibitor. Structure and living features of the potential inhibitor are as follows: two p-alkoxy benzene acrylketone units are linked to two amino groups, alcoholic hydroxyl groups and carboxyl groups or one amino group and one alcoholic hydroxyl group which are spaced by less than 8 single bonds through amide and/or ester bond, wherein compounds obtained are substrate and inhibitor of glutathione-S-transferase, namely GST; the GST catalyzes carbon-carbon bond and reduced glutathione, namely GSH, of alpha, beta-unsaturated ketone of each p-alkoxy benzene acrylketone unit in the compounds and generates a compound, namely product, through Michael addition. The product shows a stronger inhibiting efficacy on the GST, so that the compound is a GST potential inhibitor; the product has a stronger inhibiting efficacy on human GST isozyme mu in comparison with human GST isozyme alpha and pi; and the compounds can enter into cells, and can enhance inhibiting effect of cis-platinum on drug-resistant carcinoma cell growth.

Process for lowering the viscosity of highly concentrated protein solutions

A process of lowering the viscosity of a solution includes preparing a solution comprising a compound of formula I, at a concentration in the final formulation of between 10 and 250 mM, and a protein having at least one antibody fragment whose concentration is between 50 and 350 mg/mL and whose pH is between 5 and 8. The compound lowers the viscosity of the solution, which is difficult to inject, by a value of at least 15% relative to the viscosity of a solution of at least one protein having at least one antibody fragment of the same concentration and of the same pH not containing the compound.

THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS

The present invention provides thiazole derivatives as Stearoyl CoA Desaturase (SCD) inhibitors. In particular, the compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by Stearoyl CoA Desaturase