1796-86-7

Basic information

• Product Name: 3,4-dimethylpyridine 1-oxide
• CAS NO: 1796-86-7
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.1525
• Mol File: 1796-86-7.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 298.1°C at 760 mmHg
• Flash Point: 134.1°C
• Density: 1g/cm³
• Vapor Pressure: 0.00229mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: 3,4-dimethylpyridine 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethylpyridine 1-oxide(1796-86-7)
• EPA Substance Registry System: 3,4-dimethylpyridine 1-oxide(1796-86-7)

Safety Data

• Hazardous Substances Data: 1796-86-7(Hazardous Substances Data)

Upstream product

• 583-58-4 3,4-Lutidin 
• 7732-18-5 water 
• 7722-84-1 dihydrogen peroxide 

Downstream Products

• 583-58-4 3,4-Lutidin 
• 57963-11-8 4,5-dimethyl-2-aminopyridine 
• 823-39-2 dimethyl aminopyridine 
• 57261-60-6 2-cyano-3,4-dimethylpyridine 
• 1415693-83-2 N-(4,5-dimethylpyridin-2-yl)-1,1,1-trifluoro-N-phenylmethanesulfonamide 
• 1415693-84-3 N-(3,4-dimethylpyridin-2-yl)-1,1,1-trifluoro-N-phenylmethanesulfonamide 
• 343268-69-9 2-chloro-4,5-dimethyl pyridine 
• 121638-25-3 (3,4-dimethylpyridin-2-yl)methanol 
• 121638-24-2 (4,5-Dimethyl-pyridin-2-yl)-methanol 
• 1038989-14-8 4,5-dimethyl-2-(methylamino)pyridine 
• 1083168-75-5 6-chloro-4,5-dimethylpyridin-2-amine 

Relevant articles and documents

From Pyridine- N-oxides to 2-Functionalized Pyridines through Pyridyl Phosphonium Salts: An Umpolung Strategy

The reactions of pyridine-N-oxides with Ph3P under the developed conditions provide an unprecedented route to (pyridine-2-yl)phosphonium salts. Upon activation with DABCO, these salts readily serve as functionalized 2-pyridyl nucleophile equivalents. This umpolung strategy allows for the selective C2 functionalization of the pyridine ring with electrophiles, avoiding the generation and use of unstable organometallic reagents. The protocol operates at ambient temperature and tolerates sensitive functional groups, enabling the synthesis of otherwise challenging compounds.

MANUFACTURING METHOD OF OPTICAL ACTIVE SECONDARY ALCOHOL

PROBLEM TO BE SOLVED: To provide a method for manufacturing optical active secondary alcohol with high optical purity by hydrogenating a substrate carbonyl compound using a ruthenium complex with a specific optical active diphosphine compound and an amine compound of which synthesis is easy as ligands as a catalyst. SOLUTION: The manufacturing method of optical active secondary alcohol including reacting a substrate carbonyl compound (excluding 3-quinuclidinone, a 3-quinuclidinone derivative having a substituent, and ketone having an aromatic hydrocarbon group and a heterocycle) with hydrogen and/or a hydrogen-donating compound in a presence of a ruthenium complex selected from a compound represented by the following general formula (1) RuXYAB (1) [X and Y are same or different, represent a hydrogen atom or an anionic group, A represents optical active diphosphine represented by the general formula (2), and B represents an amine compound represented by the following general formula (3)]. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPO&INPIT