17962-89-9

Usage

InChI:InChI=1/C11H20N4OSi2/c1-17(2,3)15-8-14-9-10(15)12-7-13-11(9)16-18(4,5)6/h7-8H,1-6H3

Upstream product

• 68-94-0 hypoxanthine 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 86527-20-0 9-(6'-deoxy-α-L-talofuranosyl)hypoxanthine 
• 86527-19-7 7-(6'-deoxy-α-L-talofuranosyl)hypoxanthine 
• 85421-86-9 9-(6-deoxy-β-D-allofuranosyl)hypoxanthine 
• 85421-85-8 7-(6'-deoxy-β-D-allofuranosyl)hypoxanthine 
• 85421-81-4 9-<6'-deoxy-2',3',5'-tris-O-(p-nitrobenzoyl)-β-D-allofuranosyl>hypoxanthine 
• 85421-82-5 7-<6'-deoxy-2',3',5'-tris-O-(p-nitrobenzoyl)-β-D-allofuranosyl>hypoxanthine 
• 86527-18-6 9-<6'-deoxy-2',3',5'-tris-O-(p-nitrobenzoyl)-α-L-talofuranosyl>hypoxanthine 
• 86527-17-5 7-<6'-deoxy-2',3',5'-tris-O-(p-nitrobenzoyl)-α-L-talofuranosyl>hypoxanthine 

Relevant academic research and scientific papers

ANALOGS OF PURINE NUCLEOSIDES. 3. ALKOXYALKYLATION OF HYPOXANTHINE BY THE SILYL METHOD

The reaction of bis(trimethylsilyl)hypoxanthine with methyl trichloromethyl ether has been investigated. 1-Methoxymethyl-, 7-methoxymethyl, and 9-methoxymethylhypoxanthine, as well as 1,7-, 1,9-, and 3,7-bismethoxymethylhypoxanthine, have been isolated fr

Chitosan–silica sulfate nanohybrid: a highly efficient and green heterogeneous nanocatalyst for the regioselective synthesis of N-alkyl purine, pyrimidine and related N-heterocycles via presilylated method

Abstract: The presilylation of purine and pyrimidine nucleobases as well as other related N-heterocycles with HMDS utilizing chitosan–silica sulfate nanohybrid (CSSNH) is described. CSSNH is proved to be a useful, highly efficient and eco-friendly heterogeneous nanohybrid catalyst for silylation of nucleobases. The presilylated nucleobases then underwent the reaction with different sources of carbon electrophiles to afford the desired N-alkyl-substituted derivatives in good-to-excellent yields. CSSNH exhibits several advantageous involving ease of handling and preparation, low cost, reusability and environmental benignity. These unique properties render the CSSNH to be an ideal candidate for use in green industrial processes. Graphic abstract: [Figure not available: see fulltext.].

Silica sulfuric acid (SSA) as a highly efficient heterogeneous catalyst for persilylation of purine and pyrimidine nucleobases and other N-heterocycles using HMDS

Purine and pyrimidine nucleobases and other N-heterocycles have been silylated with HMDS in excellent yields in the presence of a catalytic amount of silica sulfuric acid (SSA) as a heterogeneous catalyst. SSA utilizes a shorter reaction time and higher yields of silylated nucleobases. SSA is reusable for several times without a decrease in reactivity or yield of silylated adducts. Copyright