17971-25-4Relevant academic research and scientific papers
Effective dehydrogenation of 2-pyridylmethanol derivatives catalyzed by an iron complex
Kamitani, Masahiro,Ito, Masaki,Itazaki, Masumi,Nakazawa, Hiroshi
supporting information, p. 7941 - 7944 (2014/07/08)
An unprecedented iron complex-catalyzed dehydrogenation of alcohols was achieved using CpFe(CO)2Cl with a base or CpFe(CO)(Py)(Ph) as a catalyst without sacrificing the hydrogen acceptors. This reaction effectively (up to TON 67000) converted 2-pyridylmethanol derivatives to the corresponding ketones or aldehydes. The mechanistic study is also discussed. the Partner Organisations 2014.
Friedel-Crafts hydroxyalkylation through activation of a carbonyl group using AlBr3: An easy access to pyridyl aryl/heteroaryl carbinols
Harikrishnan, Adhikesavan,Selvakumar, Jayaraman,Gnanamani, Elumalai,Bhattacharya, Suman,Ramanathan, Chinnasamy Ramaraj
supporting information, p. 563 - 567 (2013/04/10)
Aromatic electrophilic substitution of aromatic/electron rich heteroaromatic compounds with AlBr3 activated aldehydes/ketone to afford pyridyl aryl/heteroaryl or diaryl carbinols is described. The strong electron donating group dictates the regiochemical outcome of the product.
