179727-80-1Relevant academic research and scientific papers
Oxazolones: New tyrosinase inhibitors; synthesis and their structure-activity relationships
Khan, Khalid Mohammed,Mughal, Uzma Rasool,Khan, Mahmud Tareq Hassan,Zia-Ullah,Perveen, Shahnaz,Iqbal Choudhary, Muhammad
, p. 6027 - 6033 (2007/10/03)
The tyrosinase inhibitory potential of seventeen synthesized oxazolone derivatives has been evaluated and their structure-activity relationships developed in the present work. All the synthesized derivatives, 3-19, demonstrated excellent in vitro tyrosina
Conformationally constrained trytophan analogs, synthesis of (±)-(Z)- and (±)-(E)-2-amino-2,3-methano-3-(indol-3-yl)-propanoic acids
Donati, Daniele,Garzon-Aburbeh, Aaron,Natalini, Benedetto,Marchioro, Carla,Pellicciari, Roberto
, p. 9901 - 9908 (2007/10/03)
The syntheses of (±)-(Z)- and (±)-(E)-2-amino-2,3-methano-3-(indol- 3-yl)-propanoic acids (8 and 15) and reported. Key step in their preparation is the cyclopropanation of an olefinic azlactone derivative, followed by suitable deprotection sequence.
