179756-43-5

Basic information

• Product Name: (S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE
• Synonyms: (S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE;(S)-tert-Butyl 3-(4-aminophenoxy)pyrrolidine-1-carboxylate
• CAS NO: 179756-43-5
• Molecular Formula: C₁₅H₂₂N₂O₃
• Molecular Weight: 278.35
• Mol File: 179756-43-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE(179756-43-5)
• EPA Substance Registry System: (S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE(179756-43-5)

Safety Data

• Hazardous Substances Data: 179756-43-5(Hazardous Substances Data)

Usage

Description

(S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE is a pyrrolidine derivative with the molecular formula C16H24N2O3, featuring a BOC (tert-butoxycarbonyl) protecting group and an aminophenoxy group. This chemical compound is significant in organic synthesis and holds potential for various biological applications.

Uses

Used in Pharmaceutical Synthesis:
(S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of a wide range of drug candidates, contributing to the development of novel treatments for different medical conditions.
Used in Organic Synthesis:
As a building block, (S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE is used in organic synthesis for constructing more complex molecules. Its versatility in chemical reactions makes it a valuable component in the synthesis of advanced chemical compounds.
Used in Biological Research:
The presence of the aminophenoxy group in (S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE makes it potentially useful for biological applications. It can be employed in the development of new drugs, targeting specific biological systems or pathways, and in research aimed at understanding the mechanisms of various diseases.
Used in Drug Design:
(S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE can be utilized in drug design due to its structural features. (S)-1-BOC-3-(4-AMINOPHENOXY)-PYRROLIDINE can be modified and optimized to enhance its interaction with biological targets, potentially leading to the creation of more effective and selective medications.

Upstream product

• 101469-92-5 (S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 350-46-9 4-Fluoronitrobenzene 
• 1233860-29-1 (S)-tert-butyl 3-(4-nitrophenoxy)pyrrolidine-1-carboxylate 

Downstream Products

• 1036488-28-4 (1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide 
• 1229419-15-1 4-((S)-3-{4-[(2-phenyl-5-trifluoromethyl-oxazole-4-carbonyl)-amino]-phenoxy}-pyrrolidin-1-yl)-benzoic acid 
• 1229419-53-7 4-((S)-3-{4-[(2-phenyl-5-trifluoromethyl-oxazole-4-carbonyl)-amino]-phenoxy}-pyrrolidin-1-yl)-benzoic acid tert-butyl ester 
• 1085838-95-4 (S)-3-{4-[(2-phenyl-5-trifluoromethyl-oxazole-4-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid tert butyl ester 

Relevant articles and documents

NAMPT inhibitors

Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

NEW COMPOUNDS

The present invention encompassescompounds of general formula (1) wherein R1 to R4 , X and n are defined as in claim 1, which are suitable for the treatment of ailments characterised byexcessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.