17976-70-4

Basic information

• Product Name: 2-(2-hydroxyethoxy)acetaldehyde
• Synonyms: 2-(2-hydroxyethoxy)acetaldehyde
• CAS NO: 17976-70-4
• Molecular Formula: C₄H₈O₃
• Molecular Weight: 104.1
• Mol File: 17976-70-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 178 °C at 760 mmHg
• Flash Point: 75.5 °C
• Appearance: /
• Density: 1.087 g/cm³
• Vapor Pressure: 0.305mmHg at 25°C
• Refractive Index: 1.416
• PKA: 14.26±0.10(Predicted)
• CAS DataBase Reference: 2-(2-hydroxyethoxy)acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-hydroxyethoxy)acetaldehyde(17976-70-4)
• EPA Substance Registry System: 2-(2-hydroxyethoxy)acetaldehyde(17976-70-4)

Safety Data

• Hazardous Substances Data: 17976-70-4(Hazardous Substances Data)

Usage

General Description

2-(2-hydroxyethoxy)acetaldehyde, also known as glycolaldehyde, is a chemical compound with the molecular formula C4H8O3. It is a colorless liquid with a sweet, pleasant odor and is soluble in water. It is commonly used in the production of resins, plastics, and pharmaceuticals. Glycolaldehyde is also a precursor to the production of biofuels and is involved in the formation of sugars in the body. It can be synthesized through the oxidation of ethylene glycol or by the hydrolysis of glycolaldehyde diacetate. Glycolaldehyde is a versatile compound with a wide range of industrial and biological applications.

InChI:InChI=1/C4H8O3/c5-1-3-7-4-2-6/h1,6H,2-4H2

Upstream product

• 62005-55-4 2-(2,2-diethoxyethoxy)ethan-1-ol 
• 7732-18-5 water 
• 111-46-6 diethylene glycol 
• 543-75-9 1,4-dioxene 

Downstream Products

• 111974-69-7 Quetiapine 
• 6963-08-2 C₁₀H₁₂N₄O₆ 
• 6963-08-2 (2-hydroxy-ethoxy)-acetaldehyde-(2,4-dinitro-phenylhydrazone) 

Relevant articles and documents

Oxidation of diols by cetyltrimethylammonium dichromate

The oxidation kinetics of some diols have been investigated using cetyltrimethylammonium dichromate as the oxidant in dichloromethane in the presence of acetic acid and a cationic surfactant. A tentative mechanism has been proposed on the basis of (i) observed rate constant dependencies on the reactants, (ii) high negative entropy change and (iii) the kobs dependencies on surfactant concentration.

Kinetics and mechanism of oxidation of diethylene glycol by dihydroxyditellutoargentate (III) in alkaline medium

The kinetics of oxidation of diethylene glycol (DG) by dihydroxyditelluratoargentate(III) (DDA) is studied spectrophotometrically between 298.2K and 313.2K in alkaline medium. A mechanism involving a one-step two-electron transfer has been proposed The activation parameters and the rate constants of the rate-determining step are calculated.

AUTOOXIDATION OF DIETHYLENE GLYCOL.

The authors studied certain characteristics of the kinetics of accumulation of the products of autooxidation of diethylene glycol. Experiments show that both methylene groups in diethylene glycol exhibit reactivity during liquid-phase oxidation by atmospheric oxygen. During oxidation near the lower limit of the temperature range studied (90-130+ZZproducts whose formation involve cleavage of the C-O ether bond are formed at the higher rate, whereas at higher temperatures the products of conversion of the hydroxyl group predominate.