17987-91-6Relevant academic research and scientific papers
Odorless isocyanide chemistry: An integrated microfluidic system for a multistep reaction sequence
Sharma, Siddharth,Maurya, Ram Awatar,Min, Kyoung-Ik,Jeong, Guan-Young,Kim, Dong-Pyo
supporting information, p. 7564 - 7568 (2013/07/26)
Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA=N,N-diisopropylethylamine. Copyright
Synthesis of five- and six-membered lactams via solvent-free microwave Ugi reaction
Jida, Mouhamad,Malaquin, Sandra,Deprez-Poulain, Rebecca,Laconde, Guillaume,Deprez, Benoit
supporting information; experimental part, p. 5109 - 5111 (2010/11/16)
Five- and six-membered lactams were synthesized via a 4-center 3-component Ugi reaction by combining amines, isocyanides, and ketoacids under solvent-free microwave conditions. The reaction was carried out in much shorter times and the yields were improve
