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α-Hydroxy-α-(4-trifluoromethyl-phenyl)-propionic acid is a chemical compound with the molecular formula C10H9F3O4. It is a derivative of propionic acid, featuring a hydroxyl group (-OH) and a 4-trifluoromethylphenyl group attached to the α-carbon. α-Hydroxy-α-<4-trifluormethyl-phenyl>-propionsaeure is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, particularly as a building block for the development of active ingredients. Its unique structure, with the trifluoromethyl group providing increased lipophilicity and metabolic stability, makes it a valuable intermediate in the creation of various drugs and pesticides. The compound's properties, such as its reactivity and solubility, are influenced by the presence of the electron-withdrawing trifluoromethyl group, which can affect its interactions with enzymes and receptors in biological systems.

1799-81-1

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1799-81-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1799-81-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,9 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1799-81:
(6*1)+(5*7)+(4*9)+(3*9)+(2*8)+(1*1)=121
121 % 10 = 1
So 1799-81-1 is a valid CAS Registry Number.

1799-81-1Relevant academic research and scientific papers

Photocatalytic Carbinol Cation/Anion Umpolung: Direct Addition of Aromatic Aldehydes and Ketones to Carbon Dioxide

Okumura, Shintaro,Uozumi, Yasuhiro

supporting information, p. 7194 - 7198 (2021/09/22)

We have developed a new photocatalytic umpolung reaction of carbonyl compounds to generate anionic carbinol synthons. Aromatic aldehydes or ketones reacted with carbon dioxide in the presence of an iridium photocatalyst and 1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzimidazole (DMBI) as a reductant under visible-light irradiation to furnish the corresponding α-hydroxycarboxylic acids through nucleophilic addition of the resulting carbinol anions to electrophilic carbon dioxide.

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