179902-22-8

Usage

Type of compound

Derivative of benzene

Usage

Organic synthesis and chemical research

Appearance

White to off-white solid

Solubility

Soluble in organic solvents

Functional groups

Acetoxy, iodo, and methoxy

Chemical properties

Various due to functional groups

Biological properties

Useful in pharmaceutical and medicinal chemistry research

Upstream product

• 203861-62-5 2-methoxy-4-iodophenol 
• 108-24-7 acetic anhydride 
• 613-70-7 2-methoxyphenyl acetate 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 160257-85-2 5-iodo-2-methoxyphenol 
• 121042-95-3 (Z)-5-(3-tert-butyldimethylsilyloxy-4-methoxystyryl)-1,2,3-trimethoxybenzene 
• 121042-96-4 (E)-1-(3',4',5'-Trimethoxyphenyl)-2-(4''-methoxy-3''-tert-butyldimethylsiloxyphenyl)ethene 
• 186837-48-9 3-(tert-butyldimethylsilyloxy)-4-methyloxyphenyl iodide 
• 17423-63-1 3,3'-dimethoxy-4,4'-biphenoquinone 
• 4433-09-4 4,4'-Dihydroxy-3,3'-dimethoxybiphenyl 

Relevant academic research and scientific papers

New method of synthesis and biological evaluation of some combretastatin A-4 analogues

A series of novel combretastatin A-4 analogues was synthesized in 36-64% yields by Negishi cross-coupling reaction under mild conditions. The prepared compounds exhibit good cytotoxicity against HBL100 epithelial cell lines (IC50=0.022-10.31 ). Georg Thieme Verlag Stuttgart · New York.

SYNTHESIS OF 13C-LABELLED ESTROGEN ANALOGUES

There is provided a method of producing novel 13C-labelled estrogen analogues. The method preferably proceeds via an intermediate A or B or which is a mixture of (A) or (B): wherein a13C atom is located at one or more of positions 1, 2, 3 or 4 and wherein R is an optionally substituted alkane, alkene, alkyne or aryl group. Preferably R is -CH2Ph. An alternative preferred intermediate compound is 13C-resorcinol.