179914-52-4Relevant academic research and scientific papers
The shikimate pathway. Part 9. Halogenation at C-3 of the shikimate nucleus
Brettle, Roger,Cross, Richard,Frederickson, Martyn,Haslam, Edwin,MacBeath, Fiona S.,Davies, Gareth M.
, p. 10547 - 10556 (2007/10/03)
The use of (-)-shikimic acid as starting material in the syntheses of a series of C-3 halogenated derivatives including the analogous 3α- and 3β-fluoro and 3β-chloro acids is described together with the first stereospecific synthesis of (-)-3-epi-shikimic acid directly from the parent acid.
Synthesis of (3R)- and (3S)-fluoro-(4R,5R)-dihydroxy-1-cyclohexene-1- carboxylic acids: The (3R)- and (3S)-fluoro analogues of (-)-shikimic acid
Brettle,Cross,Frederickson,Haslam,MacBeath,Davies
, p. 1275 - 1278 (2007/10/03)
(3R)-and (3S)-Fluoro-(4R,5R)-dihydroxy-1-cyclohexene-1-carboxylic acids (the (3R)- and (3S)-fluoro analogues of (-)-shikimic acid) have been synthesised from (-)-shikimic acid via an intermediate epoxide (a fungal metabolite from Chalara microspora) that
