179738-33-1Relevant academic research and scientific papers
Synthesis of (-)-3(R)-amino-4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid: The 3(R)-amino analogue of (-)-shikimic acid
Brettle, Roger,Cross, Richard,Frederickson, Martyn,Haslam, Edwin,Davies, Gareth M.
, p. 291 - 294 (1996)
(-)-3(R)-Amino-4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid (the 3(R)-amino analogue of (-)-shikimic acid) has been synthesised from (-)-shikimic acid in seven steps. Copyright
Synthesis and evaluation of 2,5-dihydrochorismate analogues as inhibitors of the chorismate-utilising enzymes
Payne, Richard J.,Bulloch, Esther M. M.,Toscano, Miguel M.,Jones, Michelle A.,Kerbarh, Olivier,Abell, Chris
scheme or table, p. 2421 - 2429 (2009/09/26)
A library of 2,5-dihydrochorismate analogues were designed as inhibitors of the chorismate-utilising enzymes including anthranilate synthase, isochorismate synthase, salicylate synthase and 4-amino-4-deoxychorismate synthase. The inhibitors were synthesis
Synthesis of (3R)- and (3S)-fluoro-(4R,5R)-dihydroxy-1-cyclohexene-1- carboxylic acids: The (3R)- and (3S)-fluoro analogues of (-)-shikimic acid
Brettle,Cross,Frederickson,Haslam,MacBeath,Davies
, p. 1275 - 1278 (2007/10/03)
(3R)-and (3S)-Fluoro-(4R,5R)-dihydroxy-1-cyclohexene-1-carboxylic acids (the (3R)- and (3S)-fluoro analogues of (-)-shikimic acid) have been synthesised from (-)-shikimic acid via an intermediate epoxide (a fungal metabolite from Chalara microspora) that
The shikimate pathway. Part 8. Synthesis of (-)-3(R)-amino- 4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid: The 3(R)- amino analogue of (-)-shikimic acid
Adams,Bailey,Brettle,Cross,Frederickson,Haslam,MacBeath,Davies
, p. 8565 - 8580 (2007/10/03)
The first successful method for the introduction of nitrogenous functionality at C-3 of the shikimate nucleus has been developed and has allowed the synthesis of (-)-3(R)-amino-4(R),5(R)- dihydroxy-1-cyclohexene-1-carboxylic acid [the 3(R)-amino analogue of (-)-shikimic acid] in seven steps from the parent acid.
