179927-08-3Relevant academic research and scientific papers
Synthesis of (-)-3(R)-amino-4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid: The 3(R)-amino analogue of (-)-shikimic acid
Brettle, Roger,Cross, Richard,Frederickson, Martyn,Haslam, Edwin,Davies, Gareth M.
, p. 291 - 294 (2007/10/03)
(-)-3(R)-Amino-4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid (the 3(R)-amino analogue of (-)-shikimic acid) has been synthesised from (-)-shikimic acid in seven steps. Copyright
The shikimate pathway. Part 8. Synthesis of (-)-3(R)-amino- 4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid: The 3(R)- amino analogue of (-)-shikimic acid
Adams,Bailey,Brettle,Cross,Frederickson,Haslam,MacBeath,Davies
, p. 8565 - 8580 (2007/10/03)
The first successful method for the introduction of nitrogenous functionality at C-3 of the shikimate nucleus has been developed and has allowed the synthesis of (-)-3(R)-amino-4(R),5(R)- dihydroxy-1-cyclohexene-1-carboxylic acid [the 3(R)-amino analogue of (-)-shikimic acid] in seven steps from the parent acid.
