179930-11-1

Basic information

• Product Name: (R,E)-2-(benzo[d][1,3]dioxol-5-ylMethyleneaMino)-2-phenylethanol
• Synonyms: (R,E)-2-(benzo[d][1,3]dioxol-5-ylMethyleneaMino)-2-phenylethanol
• CAS NO: 179930-11-1
• Molecular Formula: C₁₆H₁₅NO₃
• Molecular Weight: 269.2952
• Mol File: 179930-11-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R,E)-2-(benzo[d][1,3]dioxol-5-ylMethyleneaMino)-2-phenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R,E)-2-(benzo[d][1,3]dioxol-5-ylMethyleneaMino)-2-phenylethanol(179930-11-1)
• EPA Substance Registry System: (R,E)-2-(benzo[d][1,3]dioxol-5-ylMethyleneaMino)-2-phenylethanol(179930-11-1)

Safety Data

• Hazardous Substances Data: 179930-11-1(Hazardous Substances Data)

Usage

General Description

(R,E)-2-(benzo[d][1,3]dioxol-5-ylmethyleneamino)-2-phenylethanol is a chemical compound with a complex structure. It belongs to the family of aromatic compounds and contains a benzodioxole ring. The compound also includes an amino group and a phenylethanol moiety. The (R,E) configuration indicates the stereochemistry of the compound, specifying the positions of the substituents. This chemical may have potential applications in various fields, including pharmaceuticals, organic synthesis, and materials science. The precise properties and uses of this compound would depend on its specific characteristics and behavior in different environments.

Upstream product

• 120-57-0 piperonal 
• 2549-14-6 (R)-2-Amino-1-phenylethanol 
• 122-98-5 2-Anilinoethanol 

Downstream Products

• 157341-41-8 L-694,458 

Relevant articles and documents

An efficient large-scale process for the human leukocyte elastase inhibitor, DMP 777

This report describes a new convergent, selective, and economical synthesis of DMP 777, ending with the coupling of the chiral β-lactam half of the molecule (1) to the chiral amine as the isocyanate (2). Other steps involve the coupling of the β-lactam 3 to the phenolic moiety under phase-transfer conditions, followed by resolution of the resulting piperazine derivative using a chiral acid, and recycling of the undesired enantiomer also under phase-transfer conditions. The chiral amine 4 was produced efficiently starting from (R)-α-methylbenzylamine and the corresponding butyrophenone.