179950-32-4 Usage
Description
N-(2-Carboxybenzoyl)-(-)-10,2-CAMPHORSULTAM, also known as (-)-C10-CBS or (-)-CAMPHOR-10-SULFONYL CHLORIDE, is a chiral resolving agent and a chemical compound utilized in the synthesis of peptides and peptidomimetics. It selectively binds and separates enantiomers in racemic mixtures, playing a crucial role in the pharmaceutical industry for the production of chiral drugs. Its unique structure and properties make it a valuable tool for researchers in the development of new pharmaceutical compounds and in the study of chiral molecules.
Uses
Used in Pharmaceutical Industry:
N-(2-Carboxybenzoyl)-(-)-10,2-CAMPHORSULTAM is used as a chiral resolving agent for the production of chiral drugs. It aids in the selective binding and separation of enantiomers in racemic mixtures, which is essential for the development of drugs with desired therapeutic effects and reduced side effects.
Used in Asymmetric Synthesis:
In the field of asymmetric synthesis, N-(2-Carboxybenzoyl)-(-)-10,2-CAMPHORSULTAM is used as a catalyst to promote the formation of enantiomerically pure compounds. Its unique structure enables the selective formation of one enantiomer over the other, which is crucial for the synthesis of biologically active molecules with specific stereochemistry.
Used in Research and Development:
N-(2-Carboxybenzoyl)-(-)-10,2-CAMPHORSULTAM is used as a research tool for the development of new pharmaceutical compounds and the study of chiral molecules. Its ability to selectively bind and separate enantiomers makes it valuable for understanding the role of chirality in drug action and for designing more effective and selective drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 179950-32-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,9,5 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 179950-32:
(8*1)+(7*7)+(6*9)+(5*9)+(4*5)+(3*0)+(2*3)+(1*2)=184
184 % 10 = 4
So 179950-32-4 is a valid CAS Registry Number.
InChI:InChI=1/C18H21NO3S/c1-17(2)11-7-8-18(17)10-23-19(14(18)9-11)15(20)12-5-3-4-6-13(12)16(21)22/h3-6,11,14H,7-10H2,1-2H3,(H,21,22)
179950-32-4Relevant articles and documents
Absolute conformation and chiroptical properties. VI. 2,2',3,3'- tetramethoxy-9,9'-bitriptycyl: A stereochemical analog of 1,2-disubstituted ethane with identical substituents
Toyota, Shinji,Yasutomi, Akihiro,Kojima, Hiroharu,Igarashi, Yuko,Asakura, Mitsuhiro,Oki, Michinori
, p. 2715 - 2720 (1998)
The title compound was prepared by addition of 4,5-dimethoxybenzyne to 9,9'-bianthryl. The rotational isomers, ap and ±sc, were separated by HPLC. The ±sc isomers were treated with sodium ethanethiolate to produce 3,3'- dihydroxy-2,2'-dimethoxy-9,9'-bitriptycyl, which was converted to the ester of ('S, 5R,7R)-4-[(2-carboxy)benzoyl]-3-thia-4- azatricyclo[5.2.1.01,5]decane 3,3-dioxide. The resulting diastereomers were separated by HPLC. The isomers were hydrolyzed and methylated with dimethyl sulfate to yield optically active 2,2',3,3'-tetramethoxy-9,9'- bitriptycyl. The absolute conformation of the tetramethoxy compound was determined by X-ray structure analysis of 3'-ester of (1S,5R, 7R)-4-(2- carboxybenzoyl)-3-thia-4-azatricyclo[5.2.1.01,5]decane 3,3-dioxide derived from 3-hydroxy-2,2',3'-trimethoxy-9,9'-bitriptycyl, followed by hydrolysis and then methylation. The CD spectrum of Msc-2,2',3,3'-tetramethoxy-9,9'- bitriptycyl is reported.
