180046-56-4

Basic information

• Product Name: tert-butyl (((1s,4s)-4-(cyanomethyl)cyclohexyl)methyl)carbamate
• CAS NO: 180046-56-4
• Molecular Weight: 252.357
• Mol File: 180046-56-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl (((1s,4s)-4-(cyanomethyl)cyclohexyl)methyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (((1s,4s)-4-(cyanomethyl)cyclohexyl)methyl)carbamate(180046-56-4)
• EPA Substance Registry System: tert-butyl (((1s,4s)-4-(cyanomethyl)cyclohexyl)methyl)carbamate(180046-56-4)

Safety Data

• Hazardous Substances Data: 180046-56-4(Hazardous Substances Data)

Upstream product

• 773837-37-9 sodium cyanide 
• 73094-35-6 trans-4-(hydroxymethyl)cyclohexane-1-carboxylic acid 
• 3236-47-3 (1s,4s)-cyclohexane-1,4-diyldimethanol 
• 1018674-46-8 trans-(4-Hydroxymethyl-cyclohexylmethyl)-carbamic acid tert-butyl ester 
• 162046-58-4 4-(N-tert-butyloxycarbonylaminomethyl)-cyclohexane-1-carboxylic acid 
• 3742-81-2 1-ethylcyclohexyl acetate 

Relevant articles and documents

ROR-GAMMA INHIBITORS

The present invention relates to compounds of formula I and pharmaceutical compositions comprising compounds of formula I. Compounds of Formula I are useful in treatment of inflammatory, metabolic or autoimmune diseases which are mediated by RORy.

Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient

A thiazolidinone compound represented by general formula (I) or a pharmacoligically acceptable salt thereof, STR1 wherein W represents sulfur or oxygen and X represents --N(R1)--, or alternatively X represents sulfur or oxygen and W represents --N(R1)--, and R1 represents hydrogen, alkyl or substituted alkyl; R2 and R3 are the same or different from each other, and each represents hydrogen, alkyl, substituted alkyl, aryl, or 5- or 6-membered heteroaryl; R4 represents hydrogen, alkyl or substituted C1 -C4 alkyl; R5 represents substituted cycloalkyl which may contain nitrogen, provided the substituents include --B--ONO2 (wherein B represents a single bond or alkylene) as the indispensable member and alkyl groups as optional members; and A represents a single bond or alkylene, has an excellent anti-anginal effect and thus is useful as an angina pectoris remedy or preventive.