180046-62-2

Basic information

• Product Name: Cyclohexanemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, trans-
• CAS NO: 180046-62-2
• Molecular Formula: C14H30O2Si
• Molecular Weight: 258.476
• Mol File: 180046-62-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclohexanemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, trans-(180046-62-2)
• EPA Substance Registry System: Cyclohexanemethanol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, trans-(180046-62-2)

Safety Data

• Hazardous Substances Data: 180046-62-2(Hazardous Substances Data)

Downstream Products

• 213413-30-0 (1r,4r)-4-(((tert-butyldimethylsilyl)oxy)methyl)cyclohexane-1-carbaldehyde 
• 3236-48-4 trans-1,4-Cyclohexanedimethanol 
• 1436408-63-7 C₂₃H₃₄O₃Si 
• 1436408-62-6 C₂₃H₃₁F₃O₂Si 
• 1436408-61-5 C₂₁H₃₁NO₃Si 
• 1436408-60-4 C₂₁H₃₁IOSi 
• 1436408-59-1 C₂₀H₃₁NOSi 
• 1436408-58-0 C₂₇H₃₆OSi 
• 1436408-56-8 C₂₉H₃₉ClO₃Si 
• 1436408-33-1 C₂₈H₃₁N₇O₃ 

Relevant articles and documents

Mild and selective deprotection of tert -butyl(dimethyl)silyl ethers with catalytic amounts of sodium tetrachloroaurate(III) dihydrate

A simple and mild method for the removal of tert-butyl(dimethyl)silyl (TBS) protecting groups with catalytic amounts of sodium tetrachloroaurate(III) dihydrate is described. The procedure permits selective deprotection of aliphatic TBS ethers in good to excellent yields in the presence of aromatic TBS ethers, aliphatic triisopropylsilyl ethers, aliphatic tert-butyl(diphenyl)silyl ethers, or sterically hindered aliphatic TBS ethers. Additionally, TBS ethers can also be transformed into 4-methoxybenzyl ethers or methyl ethers in one pot by using larger quantities of the catalyst and a higher reaction temperature.