180062-99-1

Basic information

• Product Name: 2-Azetidinecarboxaldehyde, 3-methoxy-1-(4-methoxyphenyl)-4-oxo-, (2R,3R)-
• CAS NO: 180062-99-1
• Molecular Formula: C12H13NO4
• Molecular Weight: 235.24
• Mol File: 180062-99-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Azetidinecarboxaldehyde, 3-methoxy-1-(4-methoxyphenyl)-4-oxo-, (2R,3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinecarboxaldehyde, 3-methoxy-1-(4-methoxyphenyl)-4-oxo-, (2R,3R)-(180062-99-1)
• EPA Substance Registry System: 2-Azetidinecarboxaldehyde, 3-methoxy-1-(4-methoxyphenyl)-4-oxo-, (2R,3R)-(180062-99-1)

Safety Data

• Hazardous Substances Data: 180062-99-1(Hazardous Substances Data)

Upstream product

• 179949-28-1 (4S,5S)-4-[(2S,3R)-3-Methoxy-1-(4-methoxy-phenyl)-4-oxo-azetidin-2-yl]-2,2-dimethyl-5-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 104-94-9 4-methoxy-aniline 
• 103239-04-9 N-(p-anisyl)-4-<(S)-2',2'-dimethyl-1',3'-dioxolan-4'-yl>-methylene-imine 
• 103174-00-1 (3R,4S)-cis-1-(p-anisyl)-3-methoxy-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>azetidin-2-one 
• 277757-29-6 (+)-(3R,4S)-4-[(S)-1,2-dihydroxyethylen]-3-methoxy-1-(p-methoxyphenyl)-2-azetidinone 
• 179949-32-7 (3R,4S)-4-((1S,2S)-1-Amino-2-hydroxy-2-phenyl-ethyl)-3-methoxy-1-(4-methoxy-phenyl)-azetidin-2-one 

Downstream Products

• 444083-12-9 (3R,4S)-4-((R)-1-Hydroxy-but-3-ynyl)-3-methoxy-1-(4-methoxy-phenyl)-azetidin-2-one 

Relevant articles and documents

Stereocontrolled access to orthogonally protected anti,anti-4- aminopiperidine-3,5-diols through chemoselective reduction of enantiopure β-lactam cyanohydrins

(Chemical Equation Presented) The cyanosilylation of enantiopure 4-oxoazetidine-2-carbaldehydes with tert-butyldimethylsilyl cyanide was promoted by either molecular sieves or catalytic amount of sodium carbonate to give O-silylated β-lactam cyanohydrins

Stereoselective allylation of 4-oxoazetidine-2-carbaldehydes. Application to the stereocontrolled synthesis of fused tricyclic β-lactams via intramolecular Diels-Alder reaction of 2-azetidinone-tethered trienes

Allylation reactions of racemic and optically pure 4-oxoazetidine-2- carbaldehydes were investigated both under anhydrous conditions and in aqueous media. Different Lewis acid or metal mediators showed varied diastereoselectivities on product formation du