180074-75-3Relevant academic research and scientific papers
Combined glycomimetic and multivalent strategies for the design of potent selectin antagonists
Roy, Rene,Park, William K. C.,Srivastava, Om P.,Foxall, Carrol
, p. 1399 - 1402 (2007/10/03)
Stepwise large scale synthesis of 3'-sulfo-Lewis(X)-Glc mimetic of the lead anti-inflammatory agent sialyl Lewis(X) in a form suitable for copolymerization with acrylamide has been achieved. The resulting water- soluble copolyacrylamide showed inhibition of binding of both L- and E- selectins in the μMolar range.
