180138-08-3

Upstream product

• 51721-77-8 2-[Bis-(1H-imidazol-4-ylmethyl)-amino]-ethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 92-62-6 proflavine 
• 180138-07-2 (6-amino-3-acridinyl)carbamic acid tert-butyl ester 
• 180138-05-0 (2-Chloro-ethyl)-bis-(1-trityl-1H-imidazol-4-ylmethyl)-amine 

Relevant academic research and scientific papers

Syntheses of imidazole-acridine conjugates as ribonuclease A mimics

As a result of efforts to mimic the activity of RNase A we report the syntheses of two novel molecules 1 and 2 containing imidazole residues conjugated to an acridine, a well known intercalator and as such these molecules simultaneously have substrate recognition and potential catalytic ability. t-RNA cleavage by 1 and 2 is reported.