180160-91-2

Basic information

• Product Name: 4-[4-(TrifluoroMethoxy)phenyl]-piperidine HCl
• Synonyms: 4-[4-(TrifluoroMethoxy)phenyl]-piperidine HCl;1-(Piperidin-4-yl)-4-(trifluoromethoxy)benzene;4-[4-(Trifluoromethoxy)phenyl]piperidine;4-(4-(TRIFLUOROMETHOXY)PHENYL)PIPERIDINE(WXC08936)
• CAS NO: 180160-91-2
• Molecular Formula: C12H14F3NO
• Molecular Weight: 245.2408696
• Mol File: 180160-91-2.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[4-(TrifluoroMethoxy)phenyl]-piperidine HCl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(TrifluoroMethoxy)phenyl]-piperidine HCl(180160-91-2)
• EPA Substance Registry System: 4-[4-(TrifluoroMethoxy)phenyl]-piperidine HCl(180160-91-2)

Safety Data

• Hazardous Substances Data: 180160-91-2(Hazardous Substances Data)

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 138647-49-1 4-Trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 462127-22-6 4-(4-(trifluoromethoxy)phenyl)-5,6-dihydropyridin-1(2H)-carboxylate tert-butyl ester 
• 169222-42-8 (4-(trifluoromethoxy)-phenyl)magnesium bromide 
• 407-14-7 1-bromo-4-(trifluoromethoxy)benzene 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 459819-54-6 4-(4-(trifluoromethoxy)phenyl)piperidine-1-formic acid tert-butyl ester 
• 681484-40-2 1,2,3,6-tetrahydro-4-(4-(trifluoromethoxy)phenyl)pyridine 

Downstream Products

• 1613627-57-8 4-(4-(4-(trifluoromethoxy)phenyl)piperidine-1-yl)benzonitrile 
• 1426520-69-5 (4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methanamine 
• 1334719-95-7 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide 
• 1334719-99-1 7-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidin-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide 

Relevant articles and documents

Nitroimidazole compound as well as preparation method and application thereof

The invention discloses a novel nitroimidazole compound as well as a preparation method and application thereof. The nitroimidazole compound has a general formula (I) shown in the specification.

Alcohols as Latent Coupling Fragments for Metallaphotoredox Catalysis: Sp3-sp2 Cross-Coupling of Oxalates with Aryl Halides

Alkyl oxalates, prepared from their corresponding alcohols, are engaged for the first time as carbon radical fragments in metallaphotoredox catalysis. In this report, we demonstrate that alcohols, native organic functional groups, can be readily activated with simple oxalyl chloride to become radical precursors in a net redox-neutral Csp3-Csp2 cross-coupling with a broad range of aryl halides. This alcohol-activation coupling is successfully applied to the functionalization of a naturally occurring steroid and the expedient synthesis of a medicinally relevant drug lead.

Design, Synthesis, and Biological Evaluation of Pyrazolo[1,5-a]pyridine-3-carboxamides as Novel Antitubercular Agents

A series of pyrazolo[1,5-a]pyridine-3-carboxamide derivatives were designed and synthesized as new anti-Mycobacterium tuberculosis (Mtb) agents. The compounds exhibit promising in vitro potency with nanomolar MIC values against the drug susceptive H37Rv s