180181-08-2Relevant academic research and scientific papers
Symmetrical anhydride-type serine protease inhibitors: Structure- activity relationship studies of human chymase inhibitors
Iijima, Kiyoko,Katada, Jun,Hayashi, Yoshio
, p. 413 - 418 (1999)
We prepared a potent and relatively selective human chymase inhibitor 9 (-), based on the study of SAR of a symmetrical anhydride-type serine protease inhibitor 1. Kinetic studies suggested that 9 (-) reacts with the Ser residue at the active site of the
Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same
-
, (2008/06/13)
Compounds of the following general formula (I) and pharmaceutically acceptable salts thereof.
