18020-61-6Relevant academic research and scientific papers
Solubility of 2,4-diamino-6-(4-pyridyl)-1,3,5-triazine in tetrahydrofuran and alcohols between 288.15 K and 318.15 K
Li, Zhizhou,Shao, Xianzhao,Wang, Wei,Zhao, Changchun,Zuo, Maifang
, (2020)
2,4-diamino-6-(4-pyridyl)-1,3,5-triazine (DAPT) was synthesized and analyzed by nuclear magnetic resonance and Fourier transform infrared spectroscopy, thermogravimetric and elemental analysis techniques as well as by high-resolution transmission electron
Synthesis of O2-and N3-(2-phosphonomethoxy)ethyl derivatives of 6-phenyl- and 6-pyridinyl-5-azacytosine
Otmar, Miroslav,Dracinsky, Martin,Jan Balzarini, Marcela Krecmerovaa,Andrei, Graciela,Snoeck, Robert
experimental part, p. 797 - 813 (2011/06/25)
A series of hydrolytically stable O2- and N3-(2- phosphonomethoxy)- ethyl (PME) derivatives of 6-phenyl, pyridin-2, -3 and -4-yl-5-azacytosines was prepared by their alkylation with diisopropyl (2-chloroethoxy)methylphosphonate followed by the deprotection. No antitumor or antiviral activity was found except for 6-(pyridin-4-yl)-1,3,5-triazine-2,4- diamine (13d) which exhibited slight activity against feline herpesvirus in CrFK cell cultures with IC50 = 6.7 μg/mL.
