127099-85-8

Basic information

• Product Name: dicyandiamide
• CAS NO: 127099-85-8
• Molecular Weight: 84.0806
• Mol File: 127099-85-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: dicyandiamide(CAS DataBase Reference)
• NIST Chemistry Reference: dicyandiamide(127099-85-8)
• EPA Substance Registry System: dicyandiamide(127099-85-8)

Safety Data

• Hazardous Substances Data: 127099-85-8(Hazardous Substances Data)

Upstream product

• 88905-87-7 azido-N-cyanoformamidinate 
• 64-17-5 ethanol 
• 45965-27-3 S-p-tolyl-isothiourea 
• 420-04-2 CYANAMID 
• 674-81-7 nitrosoguanidine 
• 14527-26-5 2-methylisothiourea sulphate 
• 2986-19-8 carbamimidothioic acid methyl ester 
• 17356-08-0 thiourea 
• 5901-56-4 N-4-nitrophenylguanidine 
• 67-64-1 acetone 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 621-85-2 S-benzyl isothiocarbamide 
• 7732-18-5 water 
• 556-90-1 pseudothiohydantoin 

Downstream Products

• 102-02-3 1-phenylbiguanide 
• 4685-18-1 2,4-diamino-6-(2-furyl)-1,3,5-triazine 
• 25007-79-8 2,4-diamino-6-(2′-pyridyl)-1,3,5-triazine 
• 16827-13-7 Isonicotinoylamino-diguanid 
• 98488-77-8 N²-furfuryl-[1,3,5]triazine-2,4-diyldiamine 
• 63071-29-4 N¹-acetyl-N³-cyanoguanidine 
• 16352-06-0 6-methyl-5-azacytosine 
• 106837-88-1 N-carbamimidoyl-N'-(4-hydroxy-phenyl)-urea 
• 99548-38-6 1-carbamimidamido-N-(4-hydroxyphenyl)methanimidamide 
• 7152-19-4 N-(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)cyanamide 
• 77747-40-1 6-Methyl-2-ureido-4(3H)-pyrimidinone 
• 1853-88-9 6-benzyl-[1,3,5]triazine-2,4-diamine 
• 68216-08-0 1-(3-methoxy-phenyl)-biguanide 
• 98554-01-9 1-(6-chlorobenzo[d]oxazol-2-yl)guanidine 

Relevant articles and documents

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A New Method for Converting Thiourea and Monosubstituted Thioureas into Cyanamides: Desulphurisation by Superoxide Ion

Superoxide ion, in aprotic media, converts thiourea and monosubstituted thioureas into cyanamides.

Nitrosation of Cyanamide: Preparation and Properties of the Elusive E- and Z-N'-Cyanodiazohydroxides

Nitrosation of cyanamide leads to unstable E/Z-cyanodiazohydroxides that easily deprotonate to E/Z-cyanodiazotates. Pursuing observations of E. Drechsel 145 years ago, the structure and reactivity of those products was determined, mainly in aqueous solution. Depending on the pH, three different thermal decomposition pathways give either N2O + HCN or N2 + HNCO. They were evaluated experimentally and by quantum mechanical calculations.

Formation of pyrimidin-2-ylcyanamide and 2-aminopyrimidine in the reaction of aniline derivatives with cyanamide and dimethylamino-1-pyridyl-2-propenone

Substituted o- and p-nitroanilines and m-benzylaminoanilines in the reaction with cyanamide failed to yield the corresponding arylguanidines, and in the presence of 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one formed 4-pyridyl-substituted pyrimidin-2-ylcyanamides and 2-amino-pyrimidines.

CRF receptor antagonists and methods relating thereto

CRF receptor antagonists are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, such as stroke. The CRF receptor antagonists of this invention have the following structure: including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein m, R, R1, R2, A, X, Y and Z are as defined herein. Compositions containing a CRF receptor antagonist in combination with a pharmaceutically acceptable carrier are also disclosed, as well as methods for use of the same.