180250-68-4

Upstream product

• 100-39-0 benzyl bromide 
• 6272-45-3 (E)-4-benzyloxycinnamic acid 
• 7400-08-0 p-Coumaric Acid 
• 78-39-7 Triethyl orthoacetate 
• 84184-52-1 (E)-3-(4-(benzyloxy)phenyl)prop-2-en-1-ol 

Downstream Products

• 180468-61-5 (S)-3-[(2S,3S)-2-Azido-3-(4-benzyloxy-phenyl)-pent-4-enoyl]-4-benzyl-oxazolidin-2-one 
• 180250-61-7 (S)-3-[(2S,3R)-2-Azido-3-(4-benzyloxy-phenyl)-pent-4-enoyl]-4-benzyl-oxazolidin-2-one 
• 180250-70-8 (2S,3S)-2-Azido-3-(4-benzyloxy-phenyl)-pent-4-enoic acid tert-butyl ester 
• 180250-62-8 (2S,3R)-2-Azido-3-(4-benzyloxy-phenyl)-pent-4-enoic acid tert-butyl ester 
• 180250-69-5 (S)-4-Benzyl-3-[(S)-3-(4-benzyloxy-phenyl)-pent-4-enoyl]-oxazolidin-2-one 
• 180250-60-6 (S)-4-Benzyl-3-[(R)-3-(4-benzyloxy-phenyl)-pent-4-enoyl]-oxazolidin-2-one 
• 180250-65-1 (2S,3R)-2-Azido-3-(4-benzyloxy-phenyl)-pent-4-enoic acid 
• 180250-66-2 (2S,3S)-2-Azido-3-(4-benzyloxy-phenyl)-pent-4-enoic acid 
• 180250-63-9 (2S,3R)-3-(4-Benzyloxy-phenyl)-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 180250-71-9 (2S,3S)-3-(4-Benzyloxy-phenyl)-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 180250-59-3 3-(4-Benzyloxy-phenyl)-pent-4-enoic acid 

Relevant academic research and scientific papers

Constrained amino acids. An approach to the synthesis of 3-substituted prolines

The synthesis of diastereomeric substituted proline peptidomimetics as conformationally restricted tyrosine derivatives 1a,b has been accomplished utilizing the intramolecular hydroboration-cycloalkylation of azido-olefins 7a,b as the key step.