180303-29-1

Upstream product

• 180303-27-9 3-(2-Benzyloxy-4-methoxy-phenyl)-5-ethoxy-3H-isobenzofuran-1-one 
• 32884-23-4 2-benzyloxy-4-methoxybenzaldehyde 
• 180303-26-8 2-(4-ethoxy-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 180303-28-0 1-Benzo[1,3]dioxol-5-yl-3-(2-benzyloxy-4-methoxy-phenyl)-5-ethoxy-1,3-dihydro-isobenzofuran-1-ol 

Relevant academic research and scientific papers

A novel regio- and stereoselective synthesis of isoindolines

The described synthesis of isomeric isoindoline dicarboxylic acid analogs 1 and 2, two potent ETA selective receptor antagonists, involves an efficient regioselective route to highly functionalized dibenzoylbenzenes and a novel methodology for the stereoselective preparation of trans and cis 1,3- disubstituted isoindolines.