180303-28-0

Upstream product

• 32884-23-4 2-benzyloxy-4-methoxybenzaldehyde 
• 180303-26-8 2-(4-ethoxy-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole 

Downstream Products

• 180303-29-1 [2-(Benzo[1,3]dioxole-5-carbonyl)-5-ethoxy-phenyl]-(2-benzyloxy-4-methoxy-phenyl)-methanone 

Relevant academic research and scientific papers

A novel regio- and stereoselective synthesis of isoindolines

The described synthesis of isomeric isoindoline dicarboxylic acid analogs 1 and 2, two potent ETA selective receptor antagonists, involves an efficient regioselective route to highly functionalized dibenzoylbenzenes and a novel methodology for the stereoselective preparation of trans and cis 1,3- disubstituted isoindolines.