180346-15-0Relevant academic research and scientific papers
Enzymatic resolution of benzothiazepine for the preparation of squalene synthetase inhibitors
Yang, Xiaojing,Buzon, Leanne,Hamanaka, Ernie,Liu, Kevin K.-C.
, p. 4447 - 4450 (2000)
A key intermediate with a 4,1-benzothiazepine skeleton, useful for the synthesis of potent squalene synthetase inhibitors, has been prepared via enzymatic resolution providing excellent yield and enantiomeric purity.
Naphthyl-benzoxazepines or -benzothiazepines as squalene synthetase inhibitors
-
, (2008/06/13)
This invention relates to certain benzoxazepinones and benzothiazepinones useful as hypocholesterolemic agents and antiatheroscierosis agents.
