180399-39-7Relevant academic research and scientific papers
v-Triazolines. XXXIX [1]. l,2,4-Triaryl-3-aminopyrroles. Unusual Reaction Products in the Pyrolysis of 5-Amino-v-triazolines and the Crystal Structure of 2-(3-Morpholin-4-yl-2,4-pyrrol-l-yl)benzonitrile
Pocar, Donato,Trimarco, Pasqualina,Bombieri, Gabriella
, p. 687 - 692 (1998)
Pyrolysis of 4-aryl-5-amino-v-triazolines affords, generally, amidines and/or benzanilides. Pyrolysis of 4-aryl-5-morpholino-v-triazolines 6, together with the expected amidines 7 and/or aryanilides 8, produced the morpholinopyrroles 9. The reaction mecha
v-Triazolines. Part 37. Rearrangement reactions of 5-amino-1-(2-formyl-, -benzoyl-, -cyano-aryl)-v-triazolines: New synthesis of 2-amino- and 2,4-diamino-quinolines and 2,4-diamino-1,7-naphthyridines
Beccalli, Egle M.,Erba, Emanuela,Gelmi, Maria Luisa,Pocar, Donato
, p. 1359 - 1364 (2007/10/03)
2-Aminoquinolines 4 were obtained in an one-pot reaction from arylacetaldehydes 1, secondary amines 2 and aryl azides 3 in refluxing benzene or xylene. 2,4-Diaminoquinolines and 2,4-diamino-1,7-naphthyridines 9 were prepared by heating arylacetaldehydes 1 with secondary amines 2 and aryl or pyridyl azides 8 and reaction with bases. Reaction intermediates were shown in certain cases to be 5-amino-v-triazolines 5 and 10 undergoing thermal rearrangement to amidines 7 and 11 followed by intramolecular base-catalysed cyclocondensation.
