1805-67-0

Basic information

• Product Name: 5-METHYLISOPHTHALALDEHYDE
• Synonyms: 5-METHYLISOPHTHALALDEHYDE;5-methyl-1,3-Benzenedicarboxaldehyde
• CAS NO: 1805-67-0
• Molecular Formula: C₉H₈O₂
• Molecular Weight: 148.15862
• Mol File: 1805-67-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-METHYLISOPHTHALALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYLISOPHTHALALDEHYDE(1805-67-0)
• EPA Substance Registry System: 5-METHYLISOPHTHALALDEHYDE(1805-67-0)

Safety Data

• Hazardous Substances Data: 1805-67-0(Hazardous Substances Data)

Upstream product

• 2747-53-7 3-methyl-3-penten-2-ol 
• 68-12-2 N,N-dimethyl-formamide 
• 4798-58-7 (E)-hex-4-en-3-ol 
• 688-99-3 5-hexen-3-ol 
• 29478-26-0 (S,R)-trans-3-hexen-2-ol 
• 4798-44-1 1-hexene-3-ol 
• 27711-63-3 1,3-bis-(hydroxymethyl)-5-methylbenzene 
• 17649-58-0 5-Methylisophthalsaeure-dimethylester 
• 31673-44-6 3-methylcyclohexa-2,5-dienecarboxylic acid 

Downstream Products

• 255375-93-0 5-methylisophthalaldehyde bis(propane-1,3-diyl dithioacetal) 
• 258834-70-7 1,3-bis(2,2':6',2''-terpyridin-4'-yl)-5-methylbenzene 
• 708974-78-1 C₉H₁₀N₂O₂ 
• 1335292-96-0 C₂₅H₂₀O₂ 
• 1361477-51-1 C₂₅H₂₈O₄ 
• 1805-71-6 N-<2,2-Dimethyl-butyryl>-6-methyl-2,4-diisopentyl-anilid 
• 1850-41-5 6-Methyl-2,4-diisopentyl-anilin 
• 1850-40-4 4-Nitro-5-methyl-1,3-diisopentyl-benzol 
• 1805-69-2 5-Methyl-1,3-diisopentyl-benzol 
• 74126-24-2 5-methylbenzene-1,3-dicarbaldehyde bis-(p-tolylsulphonylhydrazone) - benzene 1:2 complex 
• 74126-23-1 5-methylbenzene-1,3-dicarbaldehyde bis-(p-tolylsulphonylhydrazone) 
• 1805-68-1 opt.-inakt. 5-Methyl-1,3-bis-(1-hydroxy-isopentyl)-benzol 

Relevant articles and documents

DESIGN and SYNTHESIS of 1,3-BIS(3-(TRIFLUOROMETHYL)- DIAZIRIN-3-YL)PHENYLALANINE for EFFICIENT PHOTOCROSS- LINKING

Photoreactive a-amino acids are powerful chemical tools for elucidating interactions in protein networks. Typically, photophores are required for stability and generation of high-reactive species. Additionally, orientation of photophores is one of the significant issues for performing photoaffinity labeling. Therefore, we rationally designed a bis-diazirinyl-phenylalanine for which photocross- linking efficiency could be increased. In this study, we synthesized a new 1,3-bis(3-(trifluoromethyl)diazirin-3-yl)phenylalanine and demonstrated further study in terms of photoactivation.

Preparation method for synthesizing aryl aldehyde compounds by reducing aryl secondary amide or aryl secondary amide derivative through phenylsilane

The invention provides a preparation method for synthesizing aryl aldehyde compounds by reducing an aryl secondary amide or aryl secondary amide derivative through phenylsilane. In an inert atmosphere, the aryl secondary amide or an aryl secondary amide derivative is used as a raw material, phenylsilane is used as a reducing agent, 1, 4-dioxane or tetrahydrofuran or diethyl ether is used as a solvent, under the action of isopropyl magnesium chloride, a reaction is performed for 12-48 h at 40-70 DEG C, quenching, separating and purification are performed after the reaction is completed, and the aryl aldehyde product is obtained. The whole preparation process realizes one-step conversion from aryl secondary amide to aryl aldehyde, has the advantages of low cost, mild reaction conditions and high reaction yield, and avoids the use of high-temperature harsh conditions and high-cost noble metal catalysts.

AMINOGUANIDINE HYDRAZONES AS RETROMER STABILIZERS USEFUL FOR TREATING NEUROLOGICAL DISEASES

The present invention relates to novel aminoguanidine hydrazone-derivatives of Formula (I) which are effective as retromer stabilizers and useful as neuroprotecting drugs. The invention also relates to pharmaceutical compositions comprising the compounds and their use in therapy and diagnostic.

Construction of hexanuclear macrocycles by a coupling strategy from polyfunctionalized bis(terpyridines)

The construction of a heteronuclear (Ru4Fe2) hexameric metallomacrocycle with methyl- and carbonyl-functionalized bis(terpyridyl) moieties was achieved by a self-assembly of a dinuclear trimer, which was prepared in high yield via Pd

Conversion of 1,4-Dihydrobenzoic Acids to Polyformylbenzenes under Vilsmeier Reaction Conditions

1,4-Dihydrobenzoic acids 1a-e are converted by a one-pot reaction to benzene- mono-, di- and tricarboxaldehydes under Vilsmeier reaction conditions in yields ranging from 6 to 65percent.The same methodology also serves to give naphthalene-1,3-dicarboxaldehyde (2f) from 1,4-dihydro-1-naphthoic acid (1f) in 91percent yield.

5-Methylisophthalaldehyde (Uvitaldehyde) from Acyclic Unsaturated Alcohols under Vilsmeier Reaction Conditions

The Vilsmeier reaction on the acyclic unsaturated alcohols (II-VI) leads to a common product which has been characterized as 5-methylisophthalaldehyde (uvitaldehyde) (IX).The yield of IX varies from 22-35percent depending on the substrate.