180508-09-2 Usage
General Description
6-CHLORO-4-METHYLBENZIMIDAZOLE is a chemical compound with the molecular formula C8H6ClN3. It is a chlorinated derivative of benzimidazole, and its structure includes a benzene ring fused to an imidazole ring. 6-CHLORO-4-METHYLBENZIMIDAZOLE is commonly used as a building block in pharmaceutical and agrochemical synthesis, particularly in the production of anti-ulcer medications. It is a white crystalline solid that is stable under normal conditions, and it is important to handle it with care and follow proper safety protocols due to its potential health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 180508-09-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,5,0 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 180508-09:
(8*1)+(7*8)+(6*0)+(5*5)+(4*0)+(3*8)+(2*0)+(1*9)=122
122 % 10 = 2
So 180508-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H7ClN2/c1-5-2-6(9)3-7-8(5)11-4-10-7/h2-4H,1H3,(H,10,11)
180508-09-2Relevant articles and documents
Novel benzimidazole-4-carboxylic acid derivatives as potent and selective 5-HT3 receptor ligands
Lopez-Rodriguez, Maria L.,Morcillo, Ma Jose,Benhamu, Bellinda,Riaguas, Ma Dolores
, p. 1195 - 1198 (1996)
A series of benzimidazole-4-carboxylic acid derivatives was synthesized and evaluated for affinity at 5-HT3 and 5-HT4 serotoninergic receptors. Compounds 1b, c and j exhibited high affinity for the 5-HT3 receptors (K(i)=6.1, 3.7 and 4.9 nM, respectively) and no significant affinity for 5- HT4 (K(i)>1000 nM) and 5-HT(1A) (K(i)>10 000 nM) sites. Preliminary studies showed that 1c displayed activity in the two-compartment behavioural model.
