180519-80-6Relevant academic research and scientific papers
Lipase-mediated preparation of sugar building blocks
Taniguchi, Takahiko,Takeuchi, Miwako,Kadota, Kohei,ElAzab, Adel S.,Ogasawara, Kunio
, p. 1325 - 1330 (1999)
A chiral sugar building block having a dioxabicyclooctane framework has been prepared in enantiomerically pure form, along with two analogs carrying a different protecting group, in an enantiocomplementary way by employing lipase-mediated kinetic resolution as the key step.
Direct, iridium-catalyzed enantioselective and regioselective allylic etherification with aliphatic alcohols
Ueno, Satoshi,Hartwig, John F.
, p. 1928 - 1931 (2008/12/22)
(Chemical Equation Presented) From alcohol to ether: Iridium-catalyzed allylations yield α chiral ether derivatives directly from aliphatic alcohols with a simple alkali metal base (see equation). These reactions form ethers from primary, secondary, and tertiary alkoxides with high enantioselectivity. By-products from isomerization were suppressed by the use of an alkyne additive.
