18054-33-6

Basic information

• Product Name: 1,2-diphenyl-3-(trimethylsilyl)propan-2-ol
• Synonyms: 1,2-diphenyl-3-(trimethylsilyl)propan-2-ol
• CAS NO: 18054-33-6
• Molecular Weight: 284.473
• Mol File: 18054-33-6.mol

Chemical Properties

• CAS DataBase Reference: 1,2-diphenyl-3-(trimethylsilyl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-diphenyl-3-(trimethylsilyl)propan-2-ol(18054-33-6)
• EPA Substance Registry System: 1,2-diphenyl-3-(trimethylsilyl)propan-2-ol(18054-33-6)

Safety Data

• Hazardous Substances Data: 18054-33-6(Hazardous Substances Data)

Upstream product

• 13735-78-9 1-phenyl-2-(trimethylsilyl)ethanone 
• 1589-82-8 phenylmagnesium bromide 

Downstream Products

• 948-97-0 2,3-diphenyl-1-propene 
• 19643-68-6 (2S)-propane-1,2-diyldibenzene 

Relevant articles and documents

Impact on hydrogenation catalytic cycle of the R groups Cyclic feature in "r-SMS-Phos"

A series of R-SMS-Phos ligands was evaluated in the Rh(I)-catalyzed hydrogenation of a set of olefins showing a marked influence of the cyclic nature and structure of the R groups. Overall, cPen- and Cy-SMS-Phos performed efficiently, while Ph- and Bn-SMS-Phos exhibited slower kinetics and furnished lower ees also compared with C6F5CH2-SMS-Phos. The Rh(I)-(Cy-SMS-Phos) catalyst was screened under mild conditions displaying excellent enantioselectivities and high TOFs. Cases of catalysis under catalyst or substrate control were identified.