180580-35-2Relevant academic research and scientific papers
Oligosaccharides related to xyloglucan: Synthesis and X-ray crystal structure of methyl 2-O-(α-L-fucopyranosyl)-β-D-galactopyranoside
Watt, Derek K.,Brasch, Donald J.,Larsen, David S.,Melton, Laurence D.,Simpson, Jim
, p. 1 - 15 (2007/10/03)
The disaccharides methyl 2-O-(α-L-fucopyranosyl)-β-D-galactopyranoside and methyl 2-O-(α-L-fucopyranosyl)-α-D-galactopyranoside have been synthesized using the assisted halide reaction of tri-O-benzyl-α-L- fucopyranosyl bromide with methyl 3,4,6-tri-O-benzyl-β-D-galactopyranoside and methyl 3,4,6-tri-O-benzyl-α-D-galactopyranoside to construct the interresidue glycosidic linkages. A crystal structures of metyl 2-O-(α-L- fucopyranysyl)-β-D-galactopyranoside was determined using Mo-Kα X-ray data at 183 K. The space group is P1 (No. 1) with the unit cell containing two molecules of the disaccharide with unique conformations and a water molecule. The structures was refined to R = 0.0566 for 2969 reflections. The L- fucopyranosl and D-galactopyranosyl residues have the nominal 1C4 and 4C1 conformations, respectively. The interresidue torsion angels are comparable with those generated in a recent molecular modelling study.
