180593-41-3

Usage

Uses

Used in Agricultural Applications:
(4-Hydroxy-phenyl)-methyl-carbamic acid tert-butyl ester is used as a pesticide and herbicide for controlling various pests and weeds in farming. Its application is attributed to its ability to inhibit the activity of acetylcholinesterase, an enzyme crucial to the central nervous system of insects, which results in paralysis and death of the pests.
Due to the potential toxicity and environmental impact of (4-Hydroxy-phenyl)-methyl-carbamic acid tert-butyl ester, its use is regulated under strict guidelines and restrictions in many countries to ensure the safety of the environment and public health.

Upstream product

• 33576-77-1 4-Methylamino-phenol hydrobromide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 75-05-8 acetonitrile 
• 150-75-4 N-methyl-p-aminophenol 
• 1936-57-8 4-(methylamino)phenol hemisulfate 

Downstream Products

• 1178243-33-8 4-(2-methoxyethoxy)-N-methylaniline 

Relevant academic research and scientific papers

N-Methyl- N-phenylvinylsulfonamides for Cysteine-Selective Conjugation

Use of N-methyl-N-phenylvinylsulfonamides to perform chemoselective modification of cysteine-containing peptides and proteins is reported. Probes linked to the drug were applicable to prepare antibody-drug conjugates (ADCs). The drug-antibody ratio for AD

BN/CC isosterism in borazaronaphthalenes towards phosphodiesterase 10A (PDE10A) inhibitors

The application of BN/CC isosterism is explored as a method of expanding the scope of core scaffolds in biologically active compounds. The viability of potential drug candidates incorporating BN-heteroaromatic moieties was investigated through the synthesis of BN-substituted analogs to known phosphodiesterase (PDE10A) inhibitors, namely MP10 and a selection of N-methylanilide analogs. These in some cases revealed unexpectedly potent and relatively stable derivatives, providing further support for the potential of BN-incorporation in medicinal chemistry.

SUBSTITUTED QUINOLINES AND METHODS FOR TREATING CANCER

Substituted quinoline compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or ameliorate cancer are provided.

Analine derivatives as OSC inhibitors

The present invention relates to compounds of formula (I) wherein U, Y, V, W, L, X, A1, A2, A3, A4, A5 and A6 are as defined in the description and claims and pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, parasite infections, gallstones, tumors and/or hyperproliferative disorders, and/or treatment and/or prophylaxis of impaired glucose tolerance and diabetes.