180729-58-2

Upstream product

• 109-04-6 2-bromo-pyridine 
• 180978-26-1 (1S,2S,5R)-1-cyano-2-isopropyl-5-methylcyclohexane 
• 17624-36-1 2-pyridyllithium 
• 2230-82-2 menthyl tosylate 
• 1121-60-4 pyridine-2-carbaldehyde 
• 180978-33-0 (+)-(R)-[(1'S,2'S,5'R)-2'-isopropyl-5'-methylcyclohexyl](2''-pyridyl)methanol 

Downstream Products

• 180729-59-3 (-)-(S)-[(1'S,2'S,5'R)-2'-isopropyl-5'-methylcyclohexyl](2''-pyridyl)methanol 
• 180978-33-0 (+)-(R)-[(1'S,2'S,5'R)-2'-isopropyl-5'-methylcyclohexyl](2''-pyridyl)methanol 

Relevant academic research and scientific papers

Pyridyl Phosphinites and Pyridyl Phosphites from Chiral Pyridyl Alcohols - A Modular Approach

Chiral arylated pyridyl alcohols, pyridyl phosphinites and pyridyl phosphites were prepared by Suzuki arylation and/or O-functionalization with a chlorodiarylphosphane or a chlorodiarylphosphite of chiral 2-bromo-6-(1-hydroxyalkyl)pyridines or 2-(1-hydrox

Synthesis and characterisation of a suite of four chiral pyridyl alcohols derived from (-)-menthol

Reaction of menthylmagnesium chloride with pyridine-2-carbaldehyde gives a mixture of four isomeric chiral menthyl- and neomenthyl-substituted pyridylcarbinols which were fully characterised by a combination of spectroscopic and X-ray crystallographic methods. All of these alcohols catalyse the addition of diethylzinc to benzaldehyde, but with disappointing enantioselectivities.

Novel 2-(hydroxyalkyl)pyridines derived from the chiral pool

Two diastereomeric 2-(1-hydroxyalkyl)pyridines were conveniently prepared starting from (-)-menthol. The pyridylalcohols were subsequently allowed to react with phosphorus oxychloride to yield, in one step, C3-symmetric tripodal tripyridine lig