18076-17-0

Usage

Appearance

Yellow crystalline powder

Usage

Reagent in organic synthesis

Structural features

Nitro group (-NO2) attached to a phenyl ring
Methylamino group (-NH-CH3) attached to a phenyl ring
Ethanone moiety (-CO-CH3)

Industry applications

Pharmaceutical industry for drug preparation

Synthesis utility

Building block for complex organic molecules

Research and development

Study of organic reactions and development of new chemical processes

Upstream product

• 74-89-5 methylamine 
• 5465-65-6 4-chloro-3-nitroacetophenone 

Downstream Products

• 18076-19-2 3-Amino-4-methylamino-acetophenon 
• 273753-00-7 1'-bromo-4-methylamino-3-nitroacetophenone 

Relevant academic research and scientific papers

Substituted Fused Imidazole Derivatives, Pharmaceutical Compositions, and Methods of Use Thereof

Substituted fused imidazole derivatives, methods of their preparation, pharmaceutical compositions comprising a substituted fused imidazole derivative, and methods of use in treating inflammation are provided. The substituted fused imidazole derivatives may control the activity or the amount or both the activity and the amount of heme-oxygenase.

VIRAL POLYMERASE INHIBITORS

An enantiomer, diastereoisomer or tautomer of a compound, represented by formula (I): wherein either A or B is nitrogen and the other B or A is C, and the radicals R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein, or a salt or ester thereof as viral polymerase inhibitors. The compound is used as an inhibitor of RNA dependent RNA polymerases, particularly those viral polymerases within the Flaviviridae family, more particularly to HCV polymerase.

(1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders

Novel (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives, compositions containing the same, and methods of treating androgen dependent disorders in mammals.