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3-Hydroxy-2,3,4'-trimethoxyflavan-4-one is a naturally occurring flavonoid compound characterized by its unique chemical structure, which includes a flavan-4-one core with a hydroxyl group at the 3-position and three methoxy groups at the 2, 3', and 4' positions. 3-hydroxy-2,3,4'-trimethoxyflavan-4-one is known for its antioxidant properties and is found in various plants, particularly in the Rutaceae family. It plays a role in protecting plants from oxidative stress and may have potential health benefits for humans, such as anti-inflammatory and anticancer activities. However, more research is needed to fully understand its therapeutic potential and mechanisms of action.

1808-05-5

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1808-05-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1808-05-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,0 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1808-05:
(6*1)+(5*8)+(4*0)+(3*8)+(2*0)+(1*5)=75
75 % 10 = 5
So 1808-05-5 is a valid CAS Registry Number.

1808-05-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-hydroxy-2,3,4'-trimethoxyflavan-4-one

1.2 Other means of identification

Product number -
Other names 3-hydroxy-2,3-dimethoxy-2-(4-methoxy-phenyl)-chroman-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1808-05-5 SDS

1808-05-5Relevant academic research and scientific papers

Oxidation of Flavonols using lead(IV) acetate in acidic methanol

Kumar,Singh

, p. 1333 - 1337 (2007/10/02)

Oxidation of Flavonols (1a-h) and 6-propionylflavonols (1i-j) to 2,3-dimethoxy-3-hydroxyflavanones (2a-h) and 2,3-dimethoxy-3-hydroxyflavanones (2i-j), respectively using lead(IV) acetate in methanol in presence of perchloric acid and the mechanism of this transformation has been described.

Oxidation of Flavonols via Oxythallation Using Thallium(III) Acetate (TTA) and Thallium(III) Nitrate (TIN) in Methanol

Singh, Om V.,Khanna, Mahavir S.,Tanwar, Madan P.,Garg, Chandra P.,Kapoor, Ram P.

, p. 2401 - 2408 (2007/10/02)

Oxidation of flavonols (1a-f), α-naphthoflavonol (3) and 6-propionylflavonols (5a-b) to 2,3-dimethoxy-3-hydroxyflavanones (2a-f), 2,3-dimethoxy-3-hydroxy-α-naphthoflavanone (4) and 2,3-dimethoxy-3-hydroxy-6-propionylfavanones (6a-b), respectively, using thallium(III) acetate and thallium(III) nitrate in methanol is described.A mechanistic Scheme of these transformations has also been proposed.

HYPERVALENT IODINE OXIDATION OF FLAVONOLS USING BENZENE IN METHANOL

Moriarty, Robert M.,Prakash, Om,Musallam, Hikmat A.,Mahesh, Vijendra K.

, p. 1641 - 1645 (2007/10/02)

Hypervalent iodine oxidation of various flavonols (1a-1f) and α-naphthoflavonol (3) using benzene (HTIB) in methanol leads to the formation of 2,3-dimethoxy-3-hydroxyflavanones (2a-2f) and 2,3-dimethoxy-3-hydroxy-α-naphthoflavanone (4) respectively.HTIB resembles periodic acid in its oxidative behavior towards flavonols.

Reactions of Flav-2-enes and Flav-2-en-4-ones (Flavones)

Bird, T. Geoffrey C.,Brown, Ben R.,Stuart, Ian A.,Tyrrell, William R.

, p. 1831 - 1846 (2007/10/02)

Flav-2-enes, flavones, and 3-alkyl ethers of flavonols add alcohols and carboxylic acids in the presence of N-bromosuccinimide to give 2-alkoxy- and 2-acyloxy-3-bromoflavans which provide routes to cis-3-bromoflavans by reduction and to 3,4-diols by elimination and reaction with osmium tetraoxide.The 2-acyloxyflavans react with alcohols yielding 2-alkoxyflavans.Flavonols react with N-bromosuccinimide and alcohols to give bromine-free hemiacetals, the known 2,3-dialkoxy-3-hydroxyflavanones.

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