180859-17-0

Basic information

• Product Name: 2-Chloro-1-phenyl-2-tetrazol-1-yl-ethanone
• Synonyms: 2-Chloro-1-phenyl-2-tetrazol-1-yl-ethanone
• CAS NO: 180859-17-0
• Molecular Weight: 222.634
• Mol File: 180859-17-0.mol

Chemical Properties

• CAS DataBase Reference: 2-Chloro-1-phenyl-2-tetrazol-1-yl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-1-phenyl-2-tetrazol-1-yl-ethanone(180859-17-0)
• EPA Substance Registry System: 2-Chloro-1-phenyl-2-tetrazol-1-yl-ethanone(180859-17-0)

Safety Data

• Hazardous Substances Data: 180859-17-0(Hazardous Substances Data)

Upstream product

• 125850-00-2 3,5-dichloro-6-phenyl-2(H)-1,4-oxazin-2-one 
• 180858-97-3 5-Chloro-6-phenyl-tetrazolo[5,1-c][1,4]oxazin-8-one 

Relevant articles and documents

Synthesis of new 1H-tetrazoles and 1,2,3-triazoles via reactions of 3(,5)-di(chloro-2H-1,4-(benz)oxazin-2-ones with sodium azide or diazocompounds

3,5-dichloro-2H-1,4-oxazin-2-ones and 3-chloro-2H-1,4-benzoxazin-2-ones are reacted with bifunctional reagents as sodium azide and diazocompounds to yield bi(tri)cyclic tetrazolo- or triazolo fused intermediates via an intramolecular cyclisation reaction. Conversion of these lactone inter-mediates with various nucleophiles generates new substituted 1H-tetrazoles or 1,2,3-triazoles useful for pharmacological screening and for further elaboration via the α-chloroketone substituent at N-1.