18086-95-8Relevant academic research and scientific papers
A new 1,4-elimination of benzenesulfinic acid from β-keto phenylsulphones via their tosylhydrazones
Ballini, Roberto,Bosica, Giovanna,Marcantoni, Enrico
, p. 10705 - 10710 (1996)
Reaction of β-keto phenylsulphone tosylhydrazones 2 with 2 eq. of DBU, at r.t. in dichloromethane, affords α,β-unsaturated ketone tosylhydrazones 4, via the tosylazoalkenes 3 obtained by 1,4-elimination of benzenesulfinic acid.
One-Pot Synthesis of Spirocyclic or Fused Pyrazoles from Cyclic Ketones: Calcium Carbide as the Carbon Source in Ring Expansion
Yu, Yue,Chen, Yang,Huang, Wei,Wu, Wanqing,Jiang, Huanfeng
, p. 9479 - 9486 (2017/09/23)
N-Tosylhydrazones generated in situ from cyclic ketones smoothly underwent a [3 + 2] cycloaddition to afford saturated spirocyclic pyrazoles and further transformed to the fused analogues via a ring expansion in certain cases. An inexpensive and renewable
Facile one-pot synthesis of N-alkylated benzimidazole and benzotriazole from carbonyl compounds
Meng, Xu,Li, Xiaolong,Chen, Wenlin,Zhang, Yuanqing,Wang, Wen,Chen, Jinying,Song, Jinli,Feng, Huijie,Chen, Baohua
, p. 349 - 356 (2014/04/17)
An efficient one-pot N-alkylation of benzimidazole and benzotriazole from carbonyl compounds and tosylhydrazide has been accomplished via copper powder-catalyzed N - H bond insertion affording N-alkylated products in good yields. The reaction can tolerate a wide range of carbonyl compounds, such as aryl, alkyl, heterocyclic and α,β-unsaturated ketones, and aldehydes.
A Novel Reactivity of α-Nitro Ketone Tosylhydrazones with DBU. Synthesis of α,β-Unsaturated Enone Tosylhydrazones.
Ballini, Roberto,Giantomassi, Gianni
, p. 4173 - 4182 (2007/10/02)
Treatment of α-nitro ketone tosylhydrazones with DBU gives 1,4-elimination of nitrous acid affording 1-tosylazoalkenes which, under basic conditions (DBU), tautomerize to the more stable enone tosylhydrazones.The obtained tosylhydrazones may be used as st
