180901-21-7 Usage
General Description
3-Pyridazinamine, 6-(2-naphthalenylthio)- is a chemical compound with the molecular formula C16H12N4S. It is a derivative of pyridazine and contains a naphthalenylthio group. 3-Pyridazinamine, 6-(2-naphthalenylthio)- has potential applications in the field of medicinal chemistry, where it may be used as a building block for the synthesis of pharmaceutical drugs. Its specific properties and potential uses have not been extensively studied, but its structure suggests that it may have biological activity and could be of interest for further research and development in drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 180901-21-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,9,0 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 180901-21:
(8*1)+(7*8)+(6*0)+(5*9)+(4*0)+(3*1)+(2*2)+(1*1)=117
117 % 10 = 7
So 180901-21-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H11N3S/c15-13-7-8-14(17-16-13)18-12-6-5-10-3-1-2-4-11(10)9-12/h1-9H,(H2,15,16)
180901-21-7Relevant articles and documents
Imidazo[1,2-b]pyridazines. XIX syntheses and central nervous system activities of some 6-arylthio(aryloxy and alkylthio)-3(acetamidomethyl, benzamidomethyl, methoxy and unsubstituted)-2-arylimidazo[1,2-b]pyridazines
Barlin, Gordon B.,Davies, Les P.,Ireland, Stephen J.
, p. 443 - 449 (2007/10/03)
Some 6-arylthio(aryloxy and alkylthio)-3-(acetamidomethyl, benzamidomethyl, methoxy and unsubstituted)-2-arylimidazo[1,2-b]pyridazines have been prepared and examined for their ability to displace [3H]diazepam from rat brain membranes. The most active compound was 3-acetamidomethyl-2-(3′,4′-methylenedioxyphenyl)-6- phenylthioimidazo[1,2-b]pyridazine with IC50 4.4 nM. The 3-acylaminomethyl-6-(2- and 3-methoxyphenylthio)-2-phenylimidazo[1,2-b]pyridazines proved less active than their 6-phenylthio analogues, and larger substituants at the 2- and 6-positions markedly decreased binding. Significant differences in binding ability have been observed between 3-acylaminomethyl-2-aryl-6-phenylthioimidazo[1,2-b]pyridazines and the corresponding imidazo[1,2-a]pyridines.
