180998-57-6

Basic information

• Product Name: 1-acetyl-3,5-bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazole
• Synonyms: 1-acetyl-3,5-bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazole
• CAS NO: 180998-57-6
• Molecular Formula: C17H14F2N2O
• Molecular Weight: 300.3026664
• Mol File: 180998-57-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-acetyl-3,5-bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetyl-3,5-bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazole(180998-57-6)
• EPA Substance Registry System: 1-acetyl-3,5-bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazole(180998-57-6)

Safety Data

• Hazardous Substances Data: 180998-57-6(Hazardous Substances Data)

Upstream product

• 2805-56-3 (2E)-1,3-bis(4-fluorophenyl)prop-2-en-1-one 
• 64-19-7 acetic acid 
• 102692-35-3 4,4'-difluorochalcone 

Relevant articles and documents

Microwave assisted synthesis of 2-pyrazolines

A simple and efficient method has been developed for the rapid synthesis of 1-acetyl-3, 5-diaryl-2-pyrazolines 2 from chalcones 1 and hydrazine hydrate in unmodified domestic microwave oven in unsealed borosil vessels using acetic acid as energy transfer medium. Rate enhancement with improved yield, a characteristic of the synthesis under microwave irradiation has been observed in the present paper. The compounds synthesised have been characterised and compared with samples prepared by thermal methods.

New 2-pyrazolines of anticipated molluscicidal activity

A facile one-pot synthesis of 1-substituted carbamoyl- or thiocarbamoyl-2-pyrazolines 6 is described. The synthesis as well as molluscicidal activity of 1,3,5-triaryl- and 1-acetyl-3,5-diaryl-2-pyrazolines (2 and 4) are also outlined.