18102-22-2 Usage
Uses
Used in Pharmaceutical Industry:
1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is used as an intermediate in the synthesis of various pharmaceutical compounds for its ability to be further modified and incorporated into drug molecules. Its presence in the molecule can influence the pharmacological properties, such as solubility, stability, and bioavailability of the final drug product.
Used in Pesticide Industry:
In the pesticide industry, 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is used as a precursor in the production of certain pesticides. Its chemical structure can be tailored to create active ingredients that target specific pests, contributing to the development of more effective and selective pest control agents.
Used in Dye Industry:
1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is utilized in the dye industry for the synthesis of various organic dyes. Its chemical structure allows for the creation of dyes with specific color properties and stability, which are important for applications in textiles, printing, and other industries that require colorants.
Safety Considerations:
Due to its potential to cause skin and eye irritation, and harmful effects if inhaled or ingested, 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is considered hazardous. It should be handled with care, using appropriate personal protective equipment and following safety protocols to minimize exposure and potential health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 18102-22-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,1,0 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 18102-22:
(7*1)+(6*8)+(5*1)+(4*0)+(3*2)+(2*2)+(1*2)=72
72 % 10 = 2
So 18102-22-2 is a valid CAS Registry Number.
18102-22-2Relevant academic research and scientific papers
HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA
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Page/Page column 67, (2018/03/28)
The present invention relates to a compound according to general formula (I) wherein X represents N or CH; R1 is -CN, (C1-C6)alkyl, (C3-C7)cycloalkyl, (3-7 membered)heterocycloalkyl, (5-6 membered)heteroaryl, (C3-C7)cycloalkyl(C1-C4)alkyl, (3-7 membered)heterocycloalkyl-(C1-C4)alkyl or (5-6 membered)heteroaryl- (C1-C4)alkyl; R2 is halogen, cyano, (C1-C4)alkyl or (C3-C7)cycloalkyl; R3 is halogen, cyano, (C1-C4)alkyl, (C1-C4)haloalkyl or (C3-C7)cycloalkyl; R4 is (C1-C4)alkyl or (C1-C4)haloalkyl; R5 is (C1-C6)alkyl, (C3-C7)cycloalkyl, (C1-C6)alkyl-(C3-C7)cycloalkyl, (C3-C7)cycloalkyl-(C1-C6)alkyl, (3-7 membered)heterocycloalkyl, phenyl, (5-6 membered)heteroaryl or -ORa. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds and to intermediates for preparation of said compounds.
Synthesis and activity of a novel inhibitor of nonsense-mediated mRNA decay
Gotham, Victoria J. B.,Hobbs, Melanie C.,Burgin, Ryan,Turton, David,Smythe, Carl,Coldham, Iain
supporting information, p. 1559 - 1563 (2016/02/10)
During efforts to prepare the known compound NMDI1, a new tetracyclic compound, called VG1, was prepared in six steps. This compound was found to have good activity as an inhibitor of nonsense-mediated mRNA decay.
