181026-06-2

Upstream product

• 181026-04-0 C₄₈H₆₈O₂₃ 
• 181025-98-9 Acetic acid (3aR,4R,6R,7R,7aS)-7-benzyloxy-2,2-dimethyl-6-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethyl ester 
• 181025-97-8 Acetic acid (2R,3S,4S,5R,6R)-5-benzyloxy-3,4-dihydroxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl ester 
• 173314-29-9 phenyl 2-O-benzyl-1-thio-α-D-glucopyranoside 
• 181026-05-1 C₄₁H₆₂O₂₃ 
• 181025-99-0 Acetic acid (3aR,4R,6S,7R,7aS)-7-benzyloxy-6-chloro-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethyl ester 

Relevant academic research and scientific papers

Chemical approaches to bacterial vaccines. Synthesis of mycobacterial oligosaccharide-protein conjugates for use as serodiagnostics and immunogens

Di- to penta-saccharide fragments (2-5) of Polysaccharide II (PS-II) of Mycobacterium tuberculosis were synthesized in spacer-linked form in a stepwise fashion using a new glycosyl donor featuring a trans-fused isopropylidene diol-protecting group. Covalent attachment of the oligosaccharides to proteins provides semi-synthetic antigens and immunogens which are being used to probe the role of PS-II as a possible mycobacterial antigen.