18103-83-8Relevant academic research and scientific papers
A novel three-component reaction of N-fluoropyridinium salts: A facile approach to imidazo[1,2-a]pyridines
Kiselyov, Alexander S.
, p. 4487 - 4490 (2005)
The reaction of N-fluoropyridinium triflate with isonitriles in acetonitrile and propionitrile in the presence of NaBH(OAc)3 led to the formation of the corresponding imidazo[1,2-a]pyridines in 44-73% yields. The proposed reaction mechanism involves the intermediate formation of a highly reactive carbene species and apparent reduction of the pyridinium intermediate with NaBH(OAc)3 to yield the targeted heterocycles.
