181058-87-7Relevant articles and documents
COMPORTAMIENTO DE β-AMINOESTERES α,β-INSATURADOS FRENTE A 1,2-DINUCLEOFILOS NITROGENADOS
Alberola, A.,Calvo, L. A.,Ortega, A. Gonzalez,Sadaba, M. L.,Sanudo, M. C.
, p. 284 - 289 (2007/10/03)
The reaction of α,β-unsaturated β-aminoesters with monosubstituted hydrazines leaded to 1,3-disubstituted 5-pyrazolones, via 1,4 addition followed by elimination and cyclization of the corresponding intermediate.This behaviour is deduced from the data obtained from monotorized reactions at low temperatures or by the isolation of the intermediates in the reactions with 1,1-disubstituted hydrazines or semicarbazide.