181059-80-3Relevant academic research and scientific papers
Synthesis of aminophenyl and methoxyphenyl perfluoroalkyl ketones
Lee, Hyeran,Czarny, Agnieszka,Battiste, Merle A.,Strekowski, Lucjan
, p. 221 - 224 (2007/10/03)
The title compounds are obtained by direct hydrolysis of the corresponding 2/4-perfluoroalkyl-substituted anilines and anisoles by the system AcOH/HBr/H2O/Al2O3. A two-step preparation of 2/4-perfluoroacylanilines involves the treatment of the 2/4-perfluoroalkylaniline with sodium ethoxide followed by hydrolysis of the resultant diethyl acetal with hydriodic acid.
A novel synthesis of 4-perfluoroalkylquinolines and related substituted quinolines
Czarny, Agnieszka,Lee, Hyeran,Say, Martial,Strekowski, Lucjan
, p. 2089 - 2092 (2007/10/03)
In spite of inefficient hydrolysis of 1-(2-aminophenyl)-2,2,3,3,4,4,4-heptafluorobutan-1-one diethyl acetal (2), this compound undergoes readily the acid-catalyzed Friedl?nder reaction with enolizable ketones to give the corresponding quinolines (4-6). Th
Base-mediated reactions of ortho- and para-perfluoroalkylanilines
Strekowski, Lucjan,Lin, Shou-Yuan,Lee, Hyeran,Mason, J. Christian
, p. 4655 - 4658 (2007/10/03)
The title chemistry involves regioselectively a benzylic position of the perfluoroalkyl group and provides an easy access to substituted quinolines and methanes.
