181067-68-5

Basic information

• Product Name: ethyl 3-(4-chlorophenyl)-2,2-dimethyl-3-oxopropanoate
• Synonyms: ethyl 3-(4-chlorophenyl)-2,2-dimethyl-3-oxopropanoate
• CAS NO: 181067-68-5
• Molecular Weight: 254.713
• Mol File: 181067-68-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 3-(4-chlorophenyl)-2,2-dimethyl-3-oxopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(4-chlorophenyl)-2,2-dimethyl-3-oxopropanoate(181067-68-5)
• EPA Substance Registry System: ethyl 3-(4-chlorophenyl)-2,2-dimethyl-3-oxopropanoate(181067-68-5)

Safety Data

• Hazardous Substances Data: 181067-68-5(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 97-62-1 Ethyl isobutyrate 
• 600-00-0 ethyl 2-bromoisobutyrate 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 182633-13-2 3-(4-Chlorophenyl)-4,4-dimethyl-4,5-dihydropyrazol-5-one 

Relevant articles and documents

Radical N-heterocyclic carbene catalysis for β-ketocarbonyl synthesis

N-Heterocyclic carbene-catalyzed radical cross-coupling between aldehydes and α-bromoesters or α-bromoamides is described. β-Ketocarbonyl compounds having a quaternary carbon center at the α-position can be synthesized under mild reaction conditions. Both aromatic and aliphatic aldehydes are suitable acyl donors by employing proper NHC catalyst precursors.