181067-69-6

Basic information

• Product Name: ethyl 2,2-dimethyl-3-oxo-3-(p-tolyl)propanoate
• Synonyms: ethyl 2,2-dimethyl-3-oxo-3-(p-tolyl)propanoate
• CAS NO: 181067-69-6
• Molecular Weight: 234.295
• Mol File: 181067-69-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2,2-dimethyl-3-oxo-3-(p-tolyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2,2-dimethyl-3-oxo-3-(p-tolyl)propanoate(181067-69-6)
• EPA Substance Registry System: ethyl 2,2-dimethyl-3-oxo-3-(p-tolyl)propanoate(181067-69-6)

Safety Data

• Hazardous Substances Data: 181067-69-6(Hazardous Substances Data)

Upstream product

• 600-00-0 ethyl 2-bromoisobutyrate 
• 104-85-8 para-methylbenzonitrile 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 59848-47-4 1-phenyl-3-(4-methylphenyl)-4,5-dihydropyrazol-5-one 

Relevant articles and documents

Radical N-heterocyclic carbene catalysis for β-ketocarbonyl synthesis

N-Heterocyclic carbene-catalyzed radical cross-coupling between aldehydes and α-bromoesters or α-bromoamides is described. β-Ketocarbonyl compounds having a quaternary carbon center at the α-position can be synthesized under mild reaction conditions. Both aromatic and aliphatic aldehydes are suitable acyl donors by employing proper NHC catalyst precursors.