181114-74-9 Usage
General Description
1-Benzyl-3-methyl-pyrrolidin-3-carboxylic acid is a chemical compound that is often used in the synthesis of pharmaceuticals and research chemicals. It is a derivative of pyrrolidin-3-carboxylic acid, which is an important building block for a variety of bioactive compounds. The benzyl group attached to the nitrogen atom and the methyl group on the pyrrolidin-3-carboxylic acid molecule provide important functional groups for further chemical modifications and structure-activity relationship studies. 1-BENZYL-3-METHYL-PYRROLIDINE-3-CARBOXYLIC ACID has potential applications in the development of new drugs and has been studied for its antimicrobial and antiviral properties. Furthermore, it is also used in the field of organic chemistry as a chiral building block for the synthesis of complex molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 181114-74-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,1,1 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 181114-74:
(8*1)+(7*8)+(6*1)+(5*1)+(4*1)+(3*4)+(2*7)+(1*4)=109
109 % 10 = 9
So 181114-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H17NO2/c1-13(12(15)16)7-8-14(10-13)9-11-5-3-2-4-6-11/h2-6H,7-10H2,1H3,(H,15,16)
181114-74-9Relevant articles and documents
A stereoselective cyclization strategy for the preparation of γ-lactams and their use in the synthesis of α-Methyl-β-proline
Banerjee, Souvik,Smith, Justin,Smith, Jillian,Faulkner, Caleb,Masterson, Douglas S.
, p. 10925 - 10930 (2013/02/22)
A straightforward stereoselective and enantiodivergent cyclization strategy for the construction of γ-lactams is described. The cyclization strategy makes use of chiral malonic esters prepared from enantiomerically enriched monoesters of disubstituted malonic acid. The cyclization occurs with the selective displacement of a substituted benzyl alcohol as the leaving group. A Hammett study illustrates that the cyclization is under electronic control. The resulting γ-lactam can be readily converted into a novel proline analogue.
